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4-AMINO-6-HYDROXY-2-METHYLPYRIMIDINE

  • Cas number：767-16-8
  • purity：99%
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Product Details

Quality Factory Hot Selling 4-AMINO-6-HYDROXY-2-METHYLPYRIMIDINE 767-16-8 with Fast Shipping

  • Molecular Formula: C5H7N3O
  • Molecular Weight: 125.13
  • Vapor Pressure: 0.0749mmHg at 25°C 
  • Melting Point: >300 °C 
  • Refractive Index: 1.651 
  • Boiling Point: 228.1 °C at 760 mmHg 
  • PKA: 10.45±0.50(Predicted) 
  • Flash Point: 91.7 °C 
  • PSA： 72.03000 
  • Density: 1.44 g/cm3 
  • LogP: 0.65400 

4-AMINO-6-HYDROXY-2-METHYLPYRIMIDINE(Cas 767-16-8) Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 73, p. 106, 1951 DOI: 10.1021/ja01145a039

InChI:InChI=1/C5H7N3O/c1-3-7-4(6)2-5(9)8-3/h2H,1H3,(H3,6,7,8,9)

767-16-8 Relevant articles

Studies on pyrimidine derivatives. XI. Reaction of ethoxycarbonylacetamide with β-dicarbonyl compounds

Yamanaka,Komatsu,Tanji,Ogawa,Konno,Mizugaki

, p. 342 - 348,343,346 (2007/10/04)

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767-16-8 Process route

6-chloro-2-methyl-3,4-dihydropyrimidin-4-one
17551-52-9

6-chloro-2-methyl-3,4-dihydropyrimidin-4-one

6-amino-2-methylpyrimidin-4(3H)-one
767-16-8

6-amino-2-methylpyrimidin-4(3H)-one

Conditions
Conditions Yield
With ammonia; water; at 170 - 180 ℃;
acetamidine hydrochloride
124-42-5

acetamidine hydrochloride

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

6-amino-2-methylpyrimidin-4(3H)-one
767-16-8

6-amino-2-methylpyrimidin-4(3H)-one

Conditions
Conditions Yield
With sodium methylate;

767-16-8 Upstream products

  • 17551-52-9
    17551-52-9

    6-chloro-2-methyl-3,4-dihydropyrimidin-4-one

  • 143-37-3
    143-37-3

    acetamidine

  • 105-56-6
    105-56-6

    ethyl 2-cyanoacetate

  • 124-42-5
    124-42-5

    acetamidine hydrochloride

767-16-8 Downstream products

  • 45741-61-5
    45741-61-5

    5,6-diamino-2-methylpyrimidin-4(3H)-one

  • 623158-23-6
    623158-23-6

    3,6-diamino-2-methyl-3H-4-pyrimidone

  • 956825-65-3
    956825-65-3

    C13 H13 N3 O2

  • 14278-61-6
    14278-61-6

    6-amino-2,5-dimethyl-3H -pyrimidin-4-one

4-AMINO-6-HYDROXY-2-METHYLPYRIMIDINE

CAS:767-16-8

Purity:99%

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